Dr. John Gupton receives NIH award
July 26, 2012
Dr. John Gupton, Professor of Chemistry, has received an Academic Research Enhancement Award (known as an AREA or R15 grant) from the National Institutes of Health-National Cancer Institute.
This three-year grant, in the amount of $348,572 is in support of his research on “The Synthesis and Bioassay of Novel Pyrroles,” and will support Dr. Gupton, along with a postdoctoral research associate and several undergraduate student researchers as they work on this project. This continues work begun under previous NIH grants. Dr. Gupton stated in his application, “Natural products of marine origin continue to be a rich source of biologically interesting compounds and pyrrole containing marine natural products in particular have demonstrated activity as anti-tumor agents, multidrug resistant reversal agents, vascular disrupting agents, and inhibitors of HIV integrase…[W]e believe that a novel and viable clinical candidate for cancer chemotherapy may well emerge from such studies.” Dr. Gupton’s team interacts with several highly experienced collaborators at other institutions.
Dr. Gupton has been the Floyd D. and Elisabeth S. Gottwald Professor of Chemistry since 2001 and has taught at the University of Richmond since 1999. He has published numerous articles in scientific journals and has won many awards for excellence in teaching and research.
This three-year grant, in the amount of $348,572 is in support of his research on “The Synthesis and Bioassay of Novel Pyrroles,” and will support Dr. Gupton, along with a postdoctoral research associate and several undergraduate student researchers as they work on this project. This continues work begun under previous NIH grants. Dr. Gupton stated in his application, “Natural products of marine origin continue to be a rich source of biologically interesting compounds and pyrrole containing marine natural products in particular have demonstrated activity as anti-tumor agents, multidrug resistant reversal agents, vascular disrupting agents, and inhibitors of HIV integrase…[W]e believe that a novel and viable clinical candidate for cancer chemotherapy may well emerge from such studies.” Dr. Gupton’s team interacts with several highly experienced collaborators at other institutions.
Dr. Gupton has been the Floyd D. and Elisabeth S. Gottwald Professor of Chemistry since 2001 and has taught at the University of Richmond since 1999. He has published numerous articles in scientific journals and has won many awards for excellence in teaching and research.